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Wednesday, April 28, 2004

PCR No More? 

In college, we did a good deal of PCR, and I commented at the time how funny it was that here we were, casually using a technique that wasn't even imagined when we were born! And now it may be obsolete, and next year's class may get to use a technique that didn't exist when they were freshmen!

This new technology, "Bio-Bar-Code Amplification" has ever so many potential applications: clinical, diagnostic, epidemiological, and research. But, of course, it can't do everything PCR does: it can't help in amplification of an unknown gene, or be of much use in cloning. It seems to me more of a potential replacement for ELISA or other fluorescent detection systems.

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