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Monday, August 09, 2004

Fatty McAtkins, Tumor Edition 

There's been a great deal of debate about whether or not the currently trendy low-carb lifestyle is good or bad for you, or neither. A new study of women in Mexico City may be good news for low-carbers: a diet high in carbohydrates, particularly sucrose and fructose, was positively associated with breast cancer. Polyunsaturated fat consumption was negatively associated, but overall fat intake was unrelated to incidence.

The theory put forth by the authors, of an overactive insuln/IGF-1 pathway, fits nicely into the Atkins Diet, which is designed to lower this pathway's activity.

It appears pretty robust, although much more information is needed before we need to go recommending diet changes. The study is current incident/retrospective, and a prospective study is a critical follow-up.

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