Tuesday, October 11, 2005
On the surface, this seems like a no-brainer result: trauma leads to amyloid plaque formation, and plaques are associated with dementias; everyone knows getting hit in the head a lot makes you dumber. The thing is, nothing's ever that simple. These data, while convincing, are retrospective and - more challengingly - recall-based. The results are dependent on reliable memory from people with dementia. So a replication is in order.